CD38 monoclonal antibody, clone HIT2 (PerCP)
产品名称： CD38 monoclonal antibody, clone HIT2 (PerCP)
英文名称： CD38 monoclonal antibody, clone HIT2 (PerCP)
产品编号： MAB5072
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against native CD38.
- Immunogen:
- Native purified CD38 from human thymocytes in foetus.
- Host:
- Mouse
- Theoretical MW (kDa):
- 45
- Reactivity:
- Human
- Specificity:
- This antibody reacts with CD38 (T10), a 45 KDa type II transmembrane glycoprotein strongly expressed mainly on plasma cells and activated T and B lymphocytes; it is an antigenic marker of lymphoid cells.
- Form:
- Liquid
- Conjugation:
- PerCP
- Isotype:
- IgG1
- Storage Buffer:
- In PBS (0.2% BSA, 15 mM sodium azide)
- Storage Instruction:
- Store in the dark at 4°C. Do not freeze.
Avoid prolonged exposure to light.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- Flow Cytometry (10 ul in human blood cells 100 ul in whole blood or 106 cells in a suspension)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Chemotaxis of mouse bone marrow neutrophils and dendritic cells is controlled by adp-ribose, the major product generated by the CD38 enzyme reaction.
Partida-Sanchez S, Gasser A, Fliegert R, Siebrands CC, Dammermann W, Shi G, Mousseau BJ, Sumoza-Toledo A, Bhagat H, Walseth TF, Guse AH, Lund FE.J Immunol. 2007 Dec 1;179(11):7827-39.
- 2.
- CD38 induces apoptosis of a murine pro-B leukemic cell line by a tyrosine kinase-dependent but ADP-ribosyl cyclase- and NAD glycohydrolase-independent mechanism.
Lund FE, Muller-Steffner H, Romero-Ramirez H, Moreno-Garcia ME, Partida-Sanchez S, Makris M, Oppenheimer NJ, Santos-Argumedo L, Schuber F.Int Immunol. 2006 Jul;18(7):1029-42. Epub 2006 May 23.
- 3.
- Kinetic competence of the cADP-ribose-CD38 complex as an intermediate in the CD38/NAD+ glycohydrolase-catalysed reactions: implication for CD38 signalling.
Cakir-Kiefer C, Muller-Steffner H, Oppenheimer N, Schuber F.Biochem J. 2001 Sep 1;358(Pt 2):399-406.
- Application Image
- Flow Cytometry
- Entrez GeneID:
- 952
- Gene Name:
- CD38
- Gene Alias:
- T10
- Gene Description:
- CD38 molecule
- Omim ID:
- 107270
- Gene Ontology:
- Hyperlink
- Gene Summary:
- CD38 is a novel multifunctional ectoenzyme widely expressed in cells and tissues especially in leukocytes. CD38 also functions in cell adhesion,signal transduction and calcium signaling. [provided by RefSeq
- Other Designations:
- ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase,CD38 antigen,CD38 antigen (p45),cyclic ADP-ribose hydrolase
- Related Disease